BENZAMIDINE HYDROCHLORIDE HYDRATE

BENZAMIDINE HYDROCHLORIDE HYDRATE - Names and Identifiers

Name	Benzamidine hydrochloride hydrate
Synonyms	BENZAMIDINE HCL HYDRATE amino(phenyl)methaniminium BENZAMIDINIUM CHLORIDE HYDRATE BENZAMIDINE HYDROCHLORIDE HYDRATE Benzamidine hydrochloride hydrate BENZAMIDINE HYDROCHLORIDE N-HYDRATE AMIDINOBENZENE HYDROCHLORIDE HYDRATE BENZAMIDINE HYDROCHLORIDE MONOHYDRATE BENZENECARBOXIMIDAMIDE HYDROCHLORIDE HYDRATE benzenecarboximidamide,hydrate,hydrochloride
CAS	206752-36-5
EINECS	606-598-5
InChI	InChI=1/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)/p+1

BENZAMIDINE HYDROCHLORIDE HYDRATE - Physico-chemical Properties

Molecular Formula	C7H11ClN2O
Molar Mass	174.63
Melting Point	86-88°C(lit.)
Boling Point	208.5°C at 760 mmHg
Flash Point	79.9°C
Water Solubility	soluble
Solubility	H2O: soluble50mg/mL, clear to slightly hazy, colorless to faintly yellow
Vapor Presure	0.213mmHg at 25°C
Appearance	White fine crystalline powder
Color	White to off-white
BRN	3594959
PH	5 (50g/l, H2O, 20℃)
Storage Condition	2-8°C
Sensitive	Hygroscopic
MDL	MFCD00066285
Use	Peptidase inhibitor (Peptidase inhibitor). Benzamidine hydrochloride is a reversible inhibitor of trypsin, tryptase and serine protease. A concentration of about 1 mM can be used for general protease inhibition. In order to inhibit yeast protease, a concentration in the range of 0.5 - 4.0 mM can be used. It can be exchanged with pepsin inhibitor (pepstatin A) to a large extent. In addition to being a competitive substance as a powerful trypsin inhibitor, benzamidine hydrochloride has also been proved to be a powerful competitive inhibitor of thrombin and plasmin (thrombin and plasmin). It has also been found that benzamidine hydrochloride as aprotinin can effectively prevent pancreatic hyperglycemia in degenerating human plasma

BENZAMIDINE HYDROCHLORIDE HYDRATE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
RTECS	CV6260000
FLUKA BRAND F CODES	3-21
TSCA	Yes
HS Code	2925 29 00

BENZAMIDINE HYDROCHLORIDE HYDRATE - Introduction

Soluble in water and ethanol.

Last Update：2022-10-16 17:14:51

BENZAMIDINE HYDROCHLORIDE HYDRATE - Reference Information

use

peptidase inhibitor (Peptidase inhibitor). Benzamidine hydrochloride is a reversible inhibitor of trypsin, tryptase and serine protease. A concentration of about 1 mM can be used for general protease inhibition. In order to inhibit yeast protease, a concentration in the range of 0.5 - 4.0 mM can be used. It can be exchanged with pepsin inhibitor (pepstatin A) to a large extent. In addition to being a competitive substance as a powerful trypsin inhibitor, benzamidine hydrochloride has also been proved to be a powerful competitive inhibitor of thrombin and plasmin (thrombin and plasmin). It has also been found that benzamidine hydrochloride as aprotinin can effectively prevent the degradation of glucagon in degraded human plasma.

Last Update：2024-04-09 15:16:48

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